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Advancing Metabolic Disease Research with Precision and Integrated Insight

Drive confident clinical decisions with comprehensive biomarker strategies, global testing capabilities, and expert scientific partnership.

Consistency across complex metabolic trials

Metabolic disease requires a deep understanding of complex biological pathways, diverse patient populations, and the subtle changes that shape treatment response. From diabetes and obesity to rare metabolic disorders, generating meaningful clinical insight requires precise biomarker measurement, longitudinal monitoring, and the ability to connect data across multiple biological systems.

Meeting these challenges requires more than individual tests; it demands an integrated approach that connects biomarker strategy, advanced analytical technologies, and globally standardized laboratory operations.

We combine these capabilities with rich scientific expertise to generate high-quality, actionable data that strengthens your decision-making, reduces development risk, and accelerates progress toward the next therapeutic breakthrough.

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Delivering the expertise your metabolic program demands

Deep biomarker expertise across metabolic pathways

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  • Glycemic control, lipid metabolism, and inflammation markers
  • Fibrosis, liver, and bone biomarkers
  • Advanced panels for complex metabolic diseases

Integrated multi-omic capabilities

CD138 (Clone B-A38) IHC staining of Inflammatory Bone Marrow FFPE sample.
  • Genomics, transcriptomics, and proteomics
  • Ligand-binding assays and cytokine profiling
  • Flow cytometry and immune profiling
  • Tissue, histopathology, and spatial biology solutions

Global, harmonized laboratory network

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  • Standardized workflows across international laboratories
  • Scalable delivery across all clinical trial phases
  • Integrated data management and reporting

Metabolic capabilities at a glance

~90
metabolic disease clinical trials
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9
market authorizations
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~75%
trials included specialty testing
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12,600
randomized patients
Duotone_Patients

Comprehensive metabolic testing capabilities

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Metabolic biomarker testing

Measure key metabolic processes using a broad range of validated biomarker assays to support disease characterization and treatment monitoring, including:

  • Glycemic markers (HbA1c, glucose, insulin, C-peptide)
  • Lipid metabolism markers (adiponectin, leptin, lipoproteins)
  • Inflammatory and cytokine markers
  • Fibrosis and liver biomarkers for NASH/NAFLD
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Genomics and transcriptomics

Explore genetic and transcriptional drivers of metabolic disease to support biomarker discovery and patient stratification through:

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Cell and immune profiling

Characterize immune involvement in metabolic disease through detailed cellular and functional analysis, including:

  • Flow cytometry and immunophenotyping
  • Cytokine profiling and functional immune assays
  • PBMC and BMMC processing
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Advanced bioanalytical and immunoassays

Generate high-sensitivity quantitative data across metabolic pathways using robust ligand-binding assays and multiplex immunoassay platforms, including:

  • Ligand-binding assays (ELISA, MSD, ELLA) for targeted biomarker quantification
  • Multiplex cytokine panels for pathway-level analysis
  • 50+ ready-to-use biomarkers across ELISA and MSD platforms
  • Additional dormant assays available for rapid activation
CD163 (Clone EDHu-1) IHC staining of Non-Small Cell Lung Cancer FFPE sample.

Tissue and histopathology (NASH expertise)

Assess tissue-level changes and disease progression using standardized histopathology and advanced imaging approaches, including:

Global laboratory network supporting metabolic disease programs

Our globally connected laboratory network delivers consistent, high‑quality data across your clinical programs through harmonized processes and shared quality standards.

Laboratories supporting immunoassays, histopathology, and broader bioanalytical capabilities include:

  • France (Paris)
  • Belgium
  • Netherlands
  • United States (New York)
  • Canada
  • South Africa
  • China (Shanghai)
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Ready to strengthen your metabolic program?

Partner with our experts to design and deliver integrated metabolic testing strategies that drive confident decisions.

Metabolic disease FAQ