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Advancing In Situ Hybridization and Multiplex Analysis with Spatial Precision

Drive confident decisions with high-plex, spatially resolved technologies, expert scientific partnership, and globally harmonized delivery.

Turning spatial complexity into actionable biological insight

Understanding biological systems requires more than identifying individual biomarkers. It depends on seeing how multiple targets interact within intact tissue, revealing patterns that are critical to translational research and clinical development.

In situ hybridization (ISH) and multiplex technologies enable high-resolution detection of RNA and DNA and protein while preserving tissue architecture. This allows you to connect gene expression with cellular context, providing a more complete view of disease biology.

We combine advanced ISH and high-plex multiplex technologies with harmonized workflows and expert scientific support. From early assay design through clinical trial delivery, we help you generate consistent, multi-dimensional data that reflects real biological complexity.

This gives you a clearer foundation for decision-making, with data that is both reproducible and directly relevant to your program.

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Expertise built for high-dimensional tissue analysis

Advanced spatial and high-plex technologies

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  • NanoString®  gene expression and spatial profiling platforms
  • RNAscope® ISH technology spatial genomics and transcriptomics tool
  • High-plex multiplex analysis within a single tissue sample
  • Sensitive detection of RNA and DNA targets

Integrated biomarker insights

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  • Combination of ISH, multiplex, and histopathology workflows
  • Multi-modal data generation from tissue, molecular, and imaging platforms
  • Deeper biological insight through spatial context

Agile global delivery model

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  • Harmonized laboratories with standardized workflows
  • Consistent data quality across regions and study phases
  • Scalable support for multi-site clinical trials

Expert-led assay strategy

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  • Fit-for-purpose assay design aligned to study endpoints
  • Development, optimization, and validation support
  • Scientific partnership from early development through clinical trials

Comprehensive in situ hybridization and multiplex capabilities

Technology spotlight: RNAscope® ISH

High-sensitivity spatial gene expression analysis at single-cell resolution

Our tissue analysis laboratory in Montpellier, France, is a certified RNAscope® service provider through the Advanced Cell Diagnostics (ACDbio) program. This ensures consistent delivery of high-quality, reproducible in situ hybridization data aligned with rigorous industry standards.

Why RNAscope® matters for your program

RNAscope® enables precise detection and localization of RNA targets within intact tissue, combining sensitivity with spatial accuracy. This allows you to:

  • Detect RNA targets at single-cell resolution
  • Preserve spatial relationships within tissue architecture
  • Achieve high specificity with low background signal
  • Generate reliable data across complex tissue types

By linking gene expression directly to spatial context, RNAscope® provides a deeper understanding of biological mechanisms than traditional gene expression approaches.

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Bring spatial insight into your next study

Design and deliver in situ hybridization and multiplex strategies with expert scientific support, tailored to the needs of your program. Connect with our teams to get started.

Multiplex and hybridization imaging FAQ