With some therapeutics proving ineffective in as many as 75% of the patients they are expected to help, the need for personalized and precision medicine is clear. Because the use of selection biomarkers can triple drug development success rates, we have expanded our portfolio to test more than routine safety and efficacy parameters.

As your global partner for integrated clinical trial laboratory and diagnostic solutions, our goal at Cerba Research is to generate early scientific insights that optimize your protocol. Our large portfolio of next-generation assays are designed for targeted approaches or broad immune profiling with multifactorial biomarkers. Benefit from our customized service to obtain innovative, flexible, and tailored solutions grounded in expert science.

Optimize biomarker strategies for precision medicine

Beyond monitoring the efficacy of a drug by PK & PD, biomarkers are increasing in importance and evolving quickly to:

  • Guide dose selection
  • Characterize mode of action
  • Stratify patients
  • Predict drug response
  • Aid in prognosis
  • Monitor disease

Streamline your development — and ensure quality

Our quality-driven approach includes analytically validated assays and GLP- and/or CLIA-certified labs. We tailor the best possible solution that meets your requirements to:

  • Transfer assays developed in-house
  • Assess method feasibility
  • Develop and validate customized assays
  • Obtain detailed sample analyses

Our comprehensive solutions include:

  • Specialty testing
  • Scientific expertise
  • Customized and tailored assays
  • Quality assurance
  • Companion diagnostics

Whether you need off-the-shelf or customized markers, ask us how our experts can help you run your trial as smoothly as possible.

Gain insights to help solve development challenges with our integrated pharmacokinetic services

Absorption, distribution, metabolization, and excretion (ADME) are fundamental to the safety and efficacy of any drug. Pharmacokinetic (PK) and pharmacodynamic (PD) assays are powerful tools to better understand your drug’s mechanism of action (MOA) and efficacious dose regimen.

Through a strategic alliance partnership with Frontage Lab, a true leader in the field, we deliver a superlative experience in the development and implementation of PK, toxicity, bioanalytical, and biomarker analyses.

State-of-the-art platforms

  • MSD S600 Meso Scale Discovery
  • ELISA platform
  • Luminex Magpix
  • Quanterix Simoa HD1
  • Ella ProteinSimple system
  • LC-MS/MS
  • Immunohistochemistry platforms

Circulating biomarkers

Here are most of the circulating biomarkers we currently test for. Because new tests are added frequently, please reach out for our complete list.

Human Plasma
  • 4β-Hydroxcholesterol
  • α-GST
  • Aβ-40
  • Active B-12
  • Anti-lia
  • Anti-Xa
  • Adiponectin
  • Aldosterone
  • Auristatin F and Auristatin F HPA
  • bFGF
  • Brain Derived Neurotropic Factor (Free)
  • C3a (Complement 3a)
  • C4 (Complement 4)
  • C5a (Complement 5a)
  • Cholesterol
  • Cholic Acid
  • Clozapine
  • Cortisol
  • CRP
  • Cystatin C
  • DPPIV
  • Eotaxin
  • Eotaxin-3
  • Ergosterol
  • E-selectin
  • Estrone/Equiline
  • Estrone sulfate/Equiline sulfate
  • Ethyl Estradiol/Norgestimate/17-Desacetyl Norgestmate
  • Exendin 9-39
  • Factor II Activity
  • Factor V Activity
  • Factor VII Activity
  • Factor VIII Activity
  • Factor IX Activity
  • Factor Xa
  • Factor X Activity
  • Factor XI Activity
  • Factor XII Activity
  • Factor XIII Activity
  • Factor VIIIc
  • Factor IX inhibiting antibodies
  • Factor VIII inhibiting antibodies
  • FGF23
  • Fibrinogen antigen
  • FLT-1
  • Fructosamine
  • FSH (follicle stimulating hormone)
  • GM-CSF
  • GLP-1
  • Glucagon
  • ICAM-1
  • IFNγ
  • IGF-2
  • IL-1α
  • IL-1β
  • IL-2
  • IL-4
  • IL-5
  • IL-6
  • IL-8
  • IL-10
  • IL-12p70
  • IL-12/23p40
  • IL-13
  • IL-15
  • IL-16
  • IL-17A
  • IP-10
  • Lepin
  • MCP-1
  • MCP-4
  • MDC
  • MIP-1β
  • NGAL
  • PAI-1 Ag
  • PIGF
  • Protein C Activity
  • Protein C Antigen
  • Protein S Antigen free
  • Protein S Total and free
  • Protein S Activity
  • Osteocalcin
  • VWF
  • TARC
  • Tie-2
  • TNFα
  • TNFβ
  • VCAM-1
  • VEGF-A
  • VEGF-D
Human Urine
  • N2- (1-Carboxyethyl)-2’Deoxy-Guanosine (CEDG)
  • Cortisol/6β-hydroxycortisol
  • Creatine
  • CTx-II
  • Glucose
  • IL-18
  • KIM-1
  • NGAL
  • NTx
Human Serum
  • Active B-12
  • Adiponectin
  • Amyloid A
  • Apolipoprotein A2
  • Apolipoprotein C3
  • Apolipoprotein E
  • APRIL
  • ATX
  • BCMA
  • CCL18
  • Chitinase 3-like 1
  • Chromogranin A
  • CK18 M30
  • CK18 M65
  • Cortisol
  • C-peptide
  • CRP
  • CXCL13
  • E-selectin
  • Estradiol (E2)
  • Ethisterone
  • Eotaxin
  • Eotaxin-3
  • FGF-19
  • FGF-21
  • Free fatty acids
  • G-CSF
  • GDF-15
  • GM-CSF
  • Human IgG Total
  • Human β-Defensin 2 (HBD2)
  • Human IgG1
  • Human IgG2
  • Human IgG3
  • Human IgG4
  • Human 90K/MAC-2BP
  • HMGB-1
  • ICAM-1
  • IFN-α
  • IFN-γ
  • IGF-1
  • IFG-2
  • IGFPB-3
  • IL-1β
  • IL-1RA
  • IL-2
  • IL-4
  • IL-5
  • IL-6
  • IL-6 sR
  • IL-7
  • IL-8
  • IL-10
  • IL-12
  • IL-12p70
  • IL-12/23p40
  • IL-13
  • IL-15
  • IL-16
  • IL-17A
  • IL-27
  • Inhibin-B
  • IP-10
  • KL-6
  • Leptin
  • MCP-1
  • MCP-4
  • MDC
  • MIP-1α
  • MIP-1β
  • MMP-1
  • MMP-2
  • MMP-3
  • MMP-7
  • MMP-9
  • MMP-12
  • MPO
  • Osteocalcin
  • PARC
  • S100A12
  • SP-A
  • SP-B
  • SP-C
  • SP-D
  • sRF
  • TARC
  • Tie-2
  • TiMP-2
  • TK-1
  • TNFα
  • TNFβ
  • VCAM-1
  • VEGF-A
  • VEGF-CVEGF-D
Human Cell/Tissue
  • Cyp1A2
  • Cyp2B6
  • Cyp3A4
Whole Blood
  • Factor II G20210A
  • Factor V Leiden
  • HLA genotyping
Human CSF
  • Aβ-40
  • Aβ42
  • hTau Ag
  • Phospho-tau
BAL Fluid
  • ATX