Expert-led preclinical strategy and model design
- Translation of scientific questions into tailored experiments
- Selection and development of fit-for-purpose models
- Deep expertise in complex biological systems
Turning Preclinical Complexity into Translational Insight
Translate complex scientific questions into robust preclinical strategies through expert model design, advanced facilities, and integrated global support.
Overcoming the key challenges in preclinical research
Strong preclinical research starts with the right models, rigorous study design, and data that can guide future development. However, limitations in model availability, disease complexity, and evolving regulatory expectations can make generating meaningful insight challenging.
Overcoming these barriers requires more than technical execution. It demands scientific expertise, translational understanding, and a strategy tailored to your program.
We partner with you to develop preclinical strategies that are built around your program goals. We select or develop fit-for-purpose models, design robust studies, and deliver them in compliant environments that generate reliable, reproducible data.
By combining in vivo, ex vivo, and in vitro model development with preclinical efficacy and safety evaluation and scientific consultation, we help you generate the evidence needed to reduce development risk as your program advances toward clinical development.
Support throughout preclinical development
Comprehensive model portfolio
- In vivo, ex vivo, and in vitro models
- Custom model development aligned to study needs
- Continuous innovation to address emerging challenges
Advanced containment and facilities
- BSL-2 and BSL-3 laboratories
- Highly trained technical and scientific teams
- Capability to handle complex and high-risk studies
Integrated preclinical-to-clinical pathway
- Seamless transition from preclinical to clinical testing
- Integration with biomarker and laboratory services
- End-to-end support across development phases
Comprehensive preclinical capabilities
In vivo models
Access a wide range of animal models, including mice, hamsters, rabbits, and ferrets, to evaluate efficacy and safety in biologically relevant systems.
Services include:
- Vaccine efficacy
- Antiviral efficacy
- Pharmacokinetics
- Non-clinical efficacy (observing the FDA Animal Rule)
- Model development
- Customized models (immune suppression)
- Board-certified pathologist
- Full pathology, including immunostains
Ex vivo and in vitro models
Leverage alternative model systems to refine experimental design, reduce reliance on animal models, and generate early-stage insights into biological responses.
Services include:
- In vitro compounding screening
- Preclinical sample testing
- In vitro/ex vivo models for early-stage efficacy testing (the 3Rs of animal research)
Custom model development
Develop tailored preclinical models aligned to your specific pathogen, therapeutic modality, or research objective. This ensures your studies are built on relevant, fit-for-purpose systems that generate meaningful and reliable data.
Efficacy and safety evaluation
Assess treatment performance through diverse readouts, including:
- Viral or pathogen titers
- Immune responses and antibody production
- Pathology and disease progression metrics
Our preclinical laboratories
Our BSL-2 and BSL-3 laboratories provide the controlled environments needed to safely study infectious and high-risk pathogens, supporting research into diseases such as COVID-19 and other emerging viral threats.
We combine advanced containment facilities with specialist scientific expertise to deliver robust, compliant preclinical studies across a range of disciplines, including cell culture, virology, serology, and histology.
Our capabilities include:
- Mammalian cell culture
- Virus culture
- Molecular virology
- Serological analysis
- Histological processing and pre-analysis
Preclinical resources and insights
Translating Scientific Questions into Preclinical Experiments
Explore how early-stage preclinical studies support model selection, study design, and experimental planning, helping generate the foundational data needed to de-risk and guide your development strategy.
Tackling Tomorrow’s Threats: Addressing Emerging Pandemic Potential Influenza and Re‑emerging Poliovirus
Learn how preclinical models are used to assess pandemic risk, transmission dynamics, and therapeutic responses for influenza and poliovirus, supporting preparedness and infectious disease research.
